The epidermal CD1c+CD11b+ cDC2s poised in the psoriasis perilesional skin, prepare the tissue and initiate inflammation，co-work with CD207+CD11chi LCs and CD5+ T cells in the psoriatic epidermis.
In our recent manuscript we describe our approach to objectively detect opioid administration using non-invasive wearable sensors. We envision this technology will ultimately be leveraged to support safer opioid prescribing, and identify warning signs before maladaptive use patterns occur.
High body iron stores have been associated with a higher risk for diabetes, dyslipidaemia and even hypertension in adults, with defined pathophysiological mechanisms. This association has not been described in iron supplemented children, and is relevant in India with universal iron fortification.
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