Communications Biology
An open access journal from Nature Portfolio publishing high-quality research, reviews and commentary in all areas of the biological sciences, representing significant advances and bringing new biological insight to a specialized area of research.
Complete remission of diabetes mellitus
Pancreas or islet transplantation have been performed with the goal of curing diabetes mellitus. Recently, gene therapy and regenerative medicine using iPS or ES cells have also been newly proposed. However, these therapies are not sufficient for more than 500 million patients in the world 1.
Exosomes release: An additional back-up system in pathological cardiac remodeling?
Single-cell analysis of two heart failure mouse models leads us to investigate the role of exosomes during pathological hypertrophic remodeling.
How amygdala plays in obsessive-compulsive disorder: Magnetic resonance imaging reveals a specific role of amygdala subregions
Accumulating evidence show amygdala involved in obsessive-compulsive disorder(OCD). Prior studies typically examined the amygdala as a homogeneous structure. Here we segment the amygdala with connectivity-based parcellation approach and suggest disorganized amygdala subregional networks in OCD.
The connective tissue protein 'ADAMTSL3' is crucial for heart function
A new study reveals essential role of ADAMTSL3, an extracellular protein of unknown function, in maintaining cardiac structure and function in the failing heart. By regulating a central heart failure signalling pathway, ADAMTSL3 emerges as a potential therapeutic target for this deadly syndrome.
